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Active Motif Acquires Amaryllis Nucleics

Thu, 01/27/2022 - 12:21

Amaryllis' RNA-seq library prep method exploits the phenomenon of nucleic acid "breathing" to insert adapters at the 5' end of RNA, which it says saves time and money.

Certain Childhood ALL Subtypes Linked to Genetic Ancestry

Thu, 01/27/2022 - 10:49

With sequence data for thousands of cases in children and young adults, researchers identified tumor molecular subtypes that coincided with patients' genetic ancestry.

Polarized Science Confidence

Thu, 01/27/2022 - 09:40

A new survey finds that confidence in science among US adults is increasingly polarized, the Associated Press says.

Time to Sit Back and Relax

Thu, 01/27/2022 - 09:38

NPR reports that the US National Institutes of Health has transferred the last of its eligible former research chimpanzees to a sanctuary.

Omicron-Focused Vaccines

Thu, 01/27/2022 - 09:35

The New York Times reports both Pfizer-BioNTech and Moderna have launched trials of SARS-CoV-2 vaccines targeting the Omicron variant.

Nature Papers Present Cloud-Computing Analysis Approach, Transcription Factor With Role in Bacterial Genome Organization

Thu, 01/27/2022 - 09:26

In Nature this week: researchers describe the free, open-source cloud-computing infrastructure Serratus and more.

Epic Sciences, Biosplice Therapeutics Partner on Multiomic Profiling for Cancer Trials

Thu, 01/27/2022 - 09:01

Biosplice will use Epic's liquid biopsy platform in several clinical trials, including for its Cirtuvivint investigative drug for solid tumors.

Hamilton, Pacific Biosciences Partner on Automating DNA Sample Prep

Thu, 01/27/2022 - 07:45

The firms were able to obtain high molecular weight DNA from 96 samples in just a few hours, with molecules ranging in size from 50 kb to more than 200 kb.

Danaher Q4 Revenues Rise 21 Percent

Thu, 01/27/2022 - 06:11

The firm's Diagnostics segment saw growth of 29 percent during the fourth quarter and 33 percent during the full year.

COVID-19 Severity Biomarker Candidates Revealed in RNA Sequencing Study

Wed, 01/26/2022 - 11:05

The George Washington University-led study uncovered increased neutrophil activity and decreased T cell activity among patients with severe COVID-19.

Time to Act

Wed, 01/26/2022 - 09:42

A new report urges the UK to consider regulations to protect against the misuse of genomic technologies, according to the Guardian.

Fulgent Seeking Defamation Suit

Wed, 01/26/2022 - 09:40

Fulgent Genetics says it plans to sue Los Angeles County Sheriff Alex Villanueva for defamation, the Los Angeles Times reports.

Speeding Gene-Edited Crops

Wed, 01/26/2022 - 09:36

Reuters reports that China's new trial rules will make it easier to grow gene-edited crops there.

Nucleic Acids Research Papers on Viral Recombination, Pan-Cancer Mutations, SARS-CoV-2 Variability

Wed, 01/26/2022 - 09:33

In Nucleic Acids Research this week: updated pipeline to detect viral recombination, mutational patterns in tumor samples, and more.

Flatiron Health, Japanese Hospital Partner on Real-World GI Cancer Database

Wed, 01/26/2022 - 07:29

Flatiron will curate real-world data from National Cancer Center Hospital East patients to build a database for research and treatment use.

Abbott Q4 Diagnostics Revenues Grow 3 Percent, Full-Year Revenues up 25 Percent

Wed, 01/26/2022 - 07:10

The Abbott Park, Illinois-based firm's global COVID-19-related sales were $2.3 billion in the fourth quarter, including $2.1 billion from rapid testing.

Molecular Diagnostics Firm Mainz Biomed Prices $22.5M Follow-on Share Offering

Wed, 01/26/2022 - 06:37

In the first half of this year, the firm intends to launch a clinical study and begin the submission process to obtain FDA clearance for its colorectal cancer diagnostic test.

Dante Labs to Refund COVID-19 Test Customers Following UK Regulatory Investigation

Wed, 01/26/2022 - 06:27

The move comes as the UK's Competition and Markets Authority cracks down on PCR test providers for price gouging and other improper business practices.

Lifespan Linked to Lower Protein Synthesis Gene Expression

Tue, 01/25/2022 - 12:03

With the help of Mendelian randomization analyses, researchers saw signs that longevity coincides with reduced RNA polymerase- and ribosomal protein-coding gene expression.

Pathogenic Variants in Disease-Causing Genes Have Low Penetrance on Average, Study Finds

Tue, 01/25/2022 - 11:44

A biobank-based study estimated the penetrance of a number of pathogenic genetic variants to find their risk of causing disease is low.